Mango is one of the popular fruits in the world due to its attractive color, delicious taste and excellent nutritional properties. Known for its sweet fragrance and flavor, the mango has delighted the senses for more than 4000 years. A celebrated fruit, mango, now produced in most of the tropical parts of the globe.

Wednesday, August 1, 2018

Mangiferin as a diuretic

Mangiferin is the major constituent obtained from Mangifera indica (Anacardiaceae). Both truly wild mango trees belong to M. indica and M. sylvatica genera.

Mangiferin and its derived lead molecule have never qualified for use in a clinical trial despite a number of pharmacological studies that have proven its effectiveness as an antioxidant, analgesic, antidiabetic, antiproliferative, chemopreventive, radioprotective, cardiotonic, immunomodulatory, and diuretic.

Diuretics increase urinary excretion of water and electrolytes and are used to relieve oedema associated with heart failure, nephrotic syndrome or hepatic cirrhosis. Most diuretics increase urine volume by inhibiting the reabsorption of sodium and chloride ions in the renal tubule; they also modify renal handling of potassium, calcium, magnesium and urate.
Mangiferin as a diuretic
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