Mangiferin and its derived lead molecule have never qualified for use in a clinical trial despite a number of pharmacological studies that have proven its effectiveness as an antioxidant, analgesic, antidiabetic, antiproliferative, chemopreventive, radioprotective, cardiotonic, immunomodulatory, and diuretic.
Diuretics increase urinary excretion of water and electrolytes and are used to relieve oedema associated with heart failure, nephrotic syndrome or hepatic cirrhosis. Most diuretics increase urine volume by inhibiting the reabsorption of sodium and chloride ions in the renal tubule; they also modify renal handling of potassium, calcium, magnesium and urate.
Mangiferin as a diuretic
 |
| Mangiferin |
